Samah I Abohamr,1,2 Mohammad O Kattea,3 Rami M Abazid,4 Mubarak A Aldossari,2 Nayef Al Asiri,2 Ayman Uthman Alhussini,2 Khalid I Al Hussaini,5 Glowi A Alasiri,6 Asghar Ali,7 Eman Elsheikh1,8 1Department of Cardiology, College of Medicine, Tanta University Hospital, Tanta, Egypt; 2Chairman of cardiology services, Mouwasat medical group, Al-Khobar, Saudi Arabia; 3Nassau University Medical Center, Saddle Riggings » Backriggings East Meadow, NY, USA; 4Internal Medicine Department, Sault Area Hospital, Sault Ste Marie, Northern Ontario Medical School University (NOSM), Sault Ste Marie, Ontario, Canada; 5Department of Internal Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 4233-13317, Saudi Arabia; 6Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 4233-13317, Saudi Arabia; 7Clinical Biochemistry Laboratory, Department of Biochemistry, School of Chemical and Life Sciences (SCLS), Jamia Hamdard, New Delhi, 110062, India; 8Internal Medicine Department, King Faisal University, Alahsa, Saudi ArabiaCorrespondence: Khalid I Al Hussaini, Department of Internal Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 4233-13317, Saudi Arabia, Email [email protected] Asghar Ali, Clinical Biochemistry Laboratory, Department of Biochemistry, School of Chemical and Life Sciences (SCLS), Jamia Hamdard, New Delhi, 110062, India, Email asgharali@jamiahamdard.
ac.inPurpose: COVID-19 is a new disease caused by the recently discovered SARS-CoV-2 virus.The COVID-19 disease manifests in several ways and it may affect various systems, including the gastrointestinal, musculoskeletal, neurological, cardiovascular, and pulmonary systems.
Individuals who have ad-additional health conditions, such as cardiovascular disorders, are particularly more likely to experience illness and death.This study aimed to assess the clinical effect of COVID-19 on myocardial injury, as measured by troponin elevation, and to determine if this effect has an impact on the outcome.Patients and Methods: This retrospective study ONE STEP CLEANSER was conducted at King Saud Medical City.
The electronic medical records used to identify all admitted patients between March 23 and June 15, 2020, with a laboratory-confirmed positive COVID-19 diagnosis who had troponin I measured.Results: During the study period, 768 COVID-19-positive patients were hospitalized.Of those, 187 patients were excluded because the troponin level was not measured.
The remaining 581 (75.7%) had troponin I measured.Overall, 89 of 581 (15.
3%) patients died.Of those, 67.8% were in the markedly elevated cTnI group, 8.
5% were in the mildly elevated cTnI group, whereas no deaths were reported in the group with normal cTnI levels.Conclusion: Myocardial injury was observed in COVID-19-admitted patients at a significant level that warrants attention to this consequence.In older individuals with pre-existing cardiovascular comorbidities, the diagnosis of myocardial injury was linked to a higher likelihood of being admitted to the intensive care unit, experiencing a worse prognosis, and ultimately, death.
Keywords: myocardial infarction, cardiovascular comorbidities, ARDS, biomarker, cytokine storm, risk stratification.